In this course we will look into the formulation of biologics, discuss different delivery and targeting strategies as well as the test systems applied to in vitro evaluate DMPK and PD properties.
The module concerns the interaction of cells and tissues with materials and surfaces. Therefore, biological principles of cells and tissues, their extracellular matrix will and regulation mechanisms due to signalling factors will be examined. Adhesion, proliferation and differentiation as well as vascularization and biomechanical characteristics will be discussed. The role of the innate immune system in the tissue response towards a biomaterial will be highlighted. Characteristics of important biomaterials like metals, polymers and ceramics will be elucidated and current applications in various fields of life sciences will be considered. Important methods of cell and tissue culture technology will be introduced, including Bioprinting.